Impact of SARS-CoV-2 infection on lipid chemical composition in an in vivo model
The COVIPID project specifically examines how SARS-CoV-2 infection affects lipid metabolism in the intestine using the fruit fly Drosophila melanogaster as a model system.
The study focuses on the disturbances induced by the virus in the composition and accumulation of intestinal lipids. It aims to perform detailed lipid profiling of the infected intestine to identify quantitative and qualitative changes in lipids. The objective is to understand the role of lipids in the immune response to viral infection and to unveil potential strategies of SARS-CoV-2 to manipulate host lipid metabolism. This project provides crucial insights into virus-host dynamics and mechanisms of defense against viral infections.